Post: #1

Taking ibuprofen changes everything in your balls, according to a Danish study titled "Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism."

http://http://www.pnas.org/content/early...1715035115

Two caveats: they only studied short-term effects, and it was a small study. Still, the implications are shocking.

Summary:

Concern has been raised over declining male reproductive health in humans. Our study addresses this issue by extending data showing antiandrogen effects of analgesics and suggests that such compounds may be involved in adult male reproductive problems. Using a unique combination of a randomized, controlled clinical trial and ex vivo and in vitro approaches, we report a univocal depression of important aspects of testicular function, including testosterone production, after use of over-the-counter ibuprofen. The study shows that ibuprofen use results in selective transcriptional repression of endocrine cells in the human testis. This repression results in the elevation of the stimulatory pituitary hormones, resulting in a state of compensated hypogonadism, a disorder associated with adverse reproductive and physical health disorders.

Post: #2

Crap! How much of a drop and for how long are we talking about?

I use ibuprofen over paracetamol because i'm afraid of the effects on my liver.

Post: #3

Less sides than morphine they said.

Post: #4

(01-15-2018 03:08 PM)The Beast1 Wrote:  Crap! How much of a drop and for how long are we talking about?

I use ibuprofen over paracetamol because i'm afraid of the effects on my liver.

Ok, the one article that mentioned 70-year-olds seems to have exaggerated a bit. The decline was 18 % in two weeks and 23 % in six weeks of taking it every day.

Whether or not it is reversible if you have been doing it for a long time is unknown.

Post: #5

(01-15-2018 04:25 PM)Akwesi Wrote:  

(01-15-2018 03:08 PM)The Beast1 Wrote:  Crap! How much of a drop and for how long are we talking about?

I use ibuprofen over paracetamol because i'm afraid of the effects on my liver.

Ok, the one article that mentioned 70-year-olds seems to have exaggerated a bit. The decline was 18 % in two weeks and 23 % in six weeks of taking it every day.

Whether or not it is reversible if you have been doing it for a long time is unknown.

OK the article is a bit of hyperbole.

I only use ibuprofen when I need it which is very sparingly. Either a hangover or head cold.

You really should not consume ibuprofen every day. It has the potential to reduce the mucus lining of your stomach leading to ulcers. Don't ask me how I know.

I'll continue using ibuprofen on an as needed basis!

Post: #6

I take aspirin all the time, don't usually go for the other stuff. I wonder if any other NSAIDs have any side-effects that we don't know about yet.

Post: #7

Ibuprofen is the go to drug to treat joint pain and more important back pain.

Doctors are so scared of opioid addicts they will push you to Ibuprofen.

It's not even half as good as the mildest opioid.

Post: #8

All of you are taking weird ass shit over a simple cold. Why not try straining the effective herbs to get over a cold instead? Natural and with zero side effects.

Post: #9

This study seems over the top and I don't see anything wrong with taking Ibuprofen occasionally.

Just my two cents and not medical advice.

If members are dealing with most sorts of pain, I highly recommend meditation or self-hypnosis over any type of pill. The only drawback is that it can take sustained effort over a period of time to reap the benefits.

I've dealt with physical pain in my life from martial art injuries and accidents.

This ranged from day to day joint pain to extremely severe pain from multiple broken bones at one time.

If the pain is severe (major surgery etc.) by all means take what your Dr. prescribes. Unfortunately it will be some type of opioid in most cases which is terrible for you and habit forming.

It took me a long time to learn, however a lot of pain is mentally created. There are even trained hypnotists that go into surgery with no anesthesia.

I'm not sure exactly how meditation works, but for me it has.

Some articles linked.

https://www.psychologytoday.com/blog/min...-suffering

https://nccih.nih.gov/research/results/s...ation-pain

Post: #10

I agree chronic pain can really benefit from mental exercise and lifestyle optimization in general (in short: of the couch, walk in the sun).

Semi-acute pain can't be meditated away though, such as a slipped disc acting up. Opiods are really the only drugs which can offer close to 100% pain relief when you're really hurting. It's true they have sides, some are good like the opoid high, very enjoyable, some are not, such as addiction. I didn't find it too difficult to come off a mild opioid, but I did get addicted and couldn't quit cold turkey. I think doctors should tell patients more of what to expect with opiods, including the very pleasent buzz.

Post: #11

Not to derail the thread, but given the tanking t-levels, and male fertility issues happening across society...I wonder why it seems like male thirst is at an all time high?

Post: #12

"The decline was 18 % in two weeks and 23 % in six weeks of taking it every day."

I don't think even the drug makers recommend taking it every day for this long, most recommend seeing a doctor before this.

Post: #13

I don't really know about ibuprofen, paracetamol or aspirin, but that's exactly why I never take them. I see no reason to really. Most people think I'm weird when I have a headache or illness and refuse to take anything or go to a doctor.
Something has to last 2 or more days before I visit a doctor or take drugs. Even though I do have a shitload of stuff kept away somewhere. All I do in that situation is start eating a lot more fruit, vegetables and vegetable juices until I feel better.

Post: #14

(01-16-2018 04:22 PM)RedPillUK Wrote:  Most people think I'm weird when I have a headache or illness and refuse to take anything or go to a doctor.
Something has to last 2 or more days before I visit a doctor or take drugs.

This is exactly what I do. 95% of stuff passes in a day or two, whether you take something for it or not. People just take medication to feel like they're doing something about the problem.

If it's a stomach problem, people ask, "What did you eat?" as if it were possible or helpful to find the exact culprit. It's the desire for certainty in an uncertain world.

And they'll ask, "Are you taking something? What are you taking for that?" People think you're crazy if you just choose to ride it out. So when I'm sick, I just downplay it as much as possible.

Most of these drugs are just about treating the symptoms, anyway, not the cause.

There's a culture here of self-medicating, including overuse of antibiotics. Dr. Mom gives you an injection of some powerful shit, probably expired, that she got without a prescription. And then people wonder why they feel even worse. I'm betting it's their lousy diet and/or the side effects of the medication.

I can't remember that last problem that I solved by going to the doctor. They have no idea what you've got. They just write a prescription to get you on your way. Doctors are great for some stuff but there's not much they can do for basic ailments.